Enzyme mechanisms: Fickle about fluorine

February 15th, 2017 by Caitlin Deane

Nature Chemical Biology 13, 243 (2017). doi:10.1038/nchembio.2324

Author: Caitlin Deane

Synthetic biology: Synthetic gene networks that smell

February 15th, 2017 by Fahim Farzadfard

Nature Chemical Biology 13, 245 (2017). doi:10.1038/nchembio.2315

Authors: Fahim Farzadfard & Timothy K Lu

Bioengineers have endowed a consortium of human cells with an artificial sense of smell, enabling the cells to detect, quantify, and remember the presence of gaseous volatile compounds in their environment.

mRNA localization: If you have to ASH

February 15th, 2017 by Joshua M. Finkelstein

Nature Chemical Biology 13, 243 (2017). doi:10.1038/nchembio.2323

Author: Joshua M. Finkelstein

Accelerating the semisynthesis of alkaloid-based drugs through metabolic engineering

February 15th, 2017 by Amy M Ehrenworth

Nature Chemical Biology 13, 249 (2017). doi:10.1038/nchembio.2308

Authors: Amy M Ehrenworth & Pamela Peralta-Yahya

  • Posted in Nat Chem Biol, Publications
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The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme

February 13th, 2017 by Jamie L Bingaman

Nature Chemical Biology 13, 439 (2017). doi:10.1038/nchembio.2300

Authors: Jamie L Bingaman, Sixue Zhang, David R Stevens, Neela H Yennawar, Sharon Hammes-Schiffer & Philip C Bevilacqua

  • Posted in Nat Chem Biol, Publications
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Evolution of a split RNA polymerase as a versatile biosensor platform

February 13th, 2017 by Jinyue Pu

Nature Chemical Biology 13, 432 (2017). doi:10.1038/nchembio.2299

Authors: Jinyue Pu, Julia Zinkus-Boltz & Bryan C Dickinson

  • Posted in Nat Chem Biol, Publications
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An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes

February 13th, 2017 by James S Italia

Nature Chemical Biology 13, 446 (2017). doi:10.1038/nchembio.2312

Authors: James S Italia, Partha Sarathi Addy, Chester J J Wrobel, Lisa A Crawford, Marc J Lajoie, Yunan Zheng & Abhishek Chatterjee

  • Posted in Nat Chem Biol, Publications
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AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons

February 13th, 2017 by Kirill Gorshkov

Nature Chemical Biology 13, 425 (2017). doi:10.1038/nchembio.2298

Authors: Kirill Gorshkov, Sohum Mehta, Santosh Ramamurthy, Gabriele V Ronnett, Feng-Quan Zhou & Jin Zhang

  • Posted in Nat Chem Biol, Publications
  • Comments Off on AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons

Selective in vivo metabolic cell-labeling-mediated cancer targeting

February 13th, 2017 by Hua Wang

Nature Chemical Biology 13, 415 (2017). doi:10.1038/nchembio.2297

Authors: Hua Wang, Ruibo Wang, Kaimin Cai, Hua He, Yang Liu, Jonathan Yen, Zhiyu Wang, Ming Xu, Yiwen Sun, Xin Zhou, Qian Yin, Li Tang, Iwona T Dobrucki, Lawrence W Dobrucki, Eric J Chaney, Stephen A Boppart, Timothy M Fan, Stéphane Lezmi, Xuesi Chen, Lichen Yin & Jianjun Cheng

CipA and CipB as Scaffolds To Organize Proteins into Crystalline Inclusions

February 10th, 2017 by Yang Wang, Ralf Heermann and Kirsten Jung

TOC Graphic

ACS Synthetic Biology
DOI: 10.1021/acssynbio.6b00323