Human antibody-based chemically induced dimerizers for cell therapeutic applications

December 4th, 2017 by Zachary B Hill

Human antibody-based chemically induced dimerizers for cell therapeutic applications

Human antibody-based chemically induced dimerizers for cell therapeutic applications, Published online: 04 December 2017; doi:10.1038/nchembio.2529

Selections with a phage-displayed antibody library against an existing protein–small-molecule complex enabled the generation of antibody-based chemically induced dimerizers (AbCIDs) with the properties necessary for use in regulating cell therapies.
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