Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells

July 9th, 2018 by Youngnam N. Jin

Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells

Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells, Published online: 09 July 2018; doi:10.1038/s41589-018-0098-0

Primordazine inhibits poly(A)-tail-independent noncanonical translation (PAINT) in early zebrafish embryos and in mammalian cells under select conditions, an effect mediated by deadenylated 3ʹ UTRs that results in ablation of primordial germ cells.
  • Posted in Nat Chem Biol, Publications
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