Ligand binding to human prostaglandin E receptor EP<sub>4</sub> at the lipid-bilayer interface

December 3rd, 2018 by Yosuke Toyoda

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface

Ligand binding to human prostaglandin E receptor EP<sub>4</sub> at the lipid-bilayer interface, Published online: 03 December 2018; doi:10.1038/s41589-018-0131-3

The structure of human prostaglandin E receptor EP4 in complex with antagonist ONO-AE3-208 and a functional antibody reveals a ligand-binding site at the interface of the lipid bilayer that is unique among GPCRs.
  • Posted in Nat Chem Biol, Publications
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