Protein circuits reprogram cells

January 7th, 2019 by Yiqian Wu

Protein circuits reprogram cells

Protein circuits reprogram cells, Published online: 07 January 2019; doi:10.1038/s41589-018-0210-5

Two protein circuit systems, split-protease-cleavable orthogonal coiled-coil logic (SPOC logic) and circuits of hacked orthogonal modular proteases (CHOMP), have been developed to permit rapid and logic function-based control of mammalian cellular signaling.