Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals

March 25th, 2019 by Xinyi Wan

Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals

Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals, Published online: 25 March 2019; doi:10.1038/s41589-019-0244-3

An engineered biosensor, which optimizes metal-sensing and couples it to transcriptional amplification cascades that produce a fluorescent protein, was applied to build a sensitive and easy-to-use sensor for the toxic metals As3+ and Hg2+.
  • Posted in Nat Chem Biol, Publications
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