<i>O</i>-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response

August 20th, 2018 by Xingqian Zhang

O-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response

<i>O</i>-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response, Published online: 20 August 2018; doi:10.1038/s41589-018-0120-6

O-GlcNAcylation of translation initiation factor component eIF4GI blocks interactions to poly(A)-binding protein Pab1 to induce disassembly of stress granules, releasing Hsp70-induced mRNAs and leading to translation of protective proteins
  • Posted in Nat Chem Biol, Publications
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