SARS-CoV-2 M<sup>pro</sup> inhibitors and activity-based probes for patient-sample imaging

October 22nd, 2020 by Wioletta Rut

Nature Chemical Biology, Published online: 22 October 2020; doi:10.1038/s41589-020-00689-z

Screening for substrate preference of the SARS-CoV and SARS-CoV-2 main protease Mpro leads to the development of activity-based probes useful for structural analysis and for visualization of active Mpro in infected patient epithelial cells.
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