Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

April 22nd, 2019 by Wim Dejonghe

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function, Published online: 22 April 2019; doi:10.1038/s41589-019-0262-1

Affinity-based target isolation and X-ray crystallography enabled identification of the non-protonophore ES9-17 as an inhibitor of the clathrin heavy chain in plants, enabling disruption of endocytosis.
  • Posted in Nat Chem Biol, Publications
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