Protein engineering: Beating the odds

December 7th, 2015 by Uwe T Bornscheuer

Nature Chemical Biology 12, 54 (2016). doi:10.1038/nchembio.1989

Author: Uwe T Bornscheuer

Recently developed advanced microfluidics-based systems have outperformed known screening tools with respect to throughput, flexibility, sensitivity and tricks for hit recovery. This has enabled the discovery of novel and improved proteins from random mutagenesis libraries or metagenome-based sources.