Iron-sulfur proteins hiding in plain sight

June 17th, 2015 by Tracey A Rouault

Nature Chemical Biology 11, 442 (2015). doi:10.1038/nchembio.1843

Author: Tracey A Rouault

Recent studies suggest that iron-sulfur (Fe-S) proteins may be unexpectedly abundant and functionally diverse in mammalian cells, but their identification still remains difficult. The use of informatics along with traditional spectroscopic analyses could be key to discovering new Fe-S proteins and validating their functional roles.