ARGuing for a new kinase class

April 8th, 2019 by Titus J. Boggon

ARGuing for a new kinase class

ARGuing for a new kinase class, Published online: 08 April 2019; doi:10.1038/s41589-019-0272-z

Arginine protein kinases regulate bacterial signaling cascades through phosphorylation of key arginine residues. Crystal structures of the kinase McsB provide the first glimpse of how these unusual enzymes recognize their protein substrates and are allosterically regulated.