Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis

August 27th, 2018 by Takaaki Taniguchi

Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis

Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis, Published online: 27 August 2018; doi:10.1038/s41589-018-0119-z

A comparative genomic approach identified a novel acetate-dependent tRNA-modifying enzyme that catalyzes RNA acetylation with a mechanism similar to tRNA aminoacylation. This modification maintains decoding fidelity in protein synthesis.
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