Anti-HIV agents inspired by antibodies

April 22nd, 2020 by Shan Su

Nature Chemical Biology, Published online: 22 April 2020; doi:10.1038/s41589-020-0521-1

Emergence of drug resistance limits the efficacy of HIV drugs, which currently requires life-long administration. In vitro high-throughput screening for competition with a broadly neutralizing antibody of HIV identified a small molecule that extends the strategies for targeting HIV.