Comparative tRNA sequencing and RNA mass spectrometry for surveying tRNA modifications

June 8th, 2020 by Satoshi Kimura

Nature Chemical Biology, Published online: 08 June 2020; doi:10.1038/s41589-020-0558-1

A combination of tRNA sequencing and mass spectrometry was developed to profile tRNA modification enabling identification of a new modification acacp3U and the presence of cytosine-to-pseudouracil RNA editing in Vibrio cholerae.
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