Selective regulation of human TRAAK channels by biologically active phospholipids

September 28th, 2020 by Samantha Schrecke

Nature Chemical Biology, Published online: 28 September 2020; doi:10.1038/s41589-020-00659-5

Native ion mobility mass spectrometry reveals two isoforms of the two-pore domain K+ channel K2P4.1 have distinct binding preferences for lipids and show a relationship between the strength of individual lipid binding events and channel activity.
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