Pharmacodynamics: Which trails are your drugs taking?

April 20th, 2015 by Rumin Zhang

Nature Chemical Biology 11, 382 (2015). doi:10.1038/nchembio.1795

Author: Rumin Zhang

Binding kinetics (BK) has an indispensable role in pharmacodynamics (PD). Incorporating slow BK into a mechanistic PD model is shown to have predictive value for in vitro cellular and in vivo animal antibacterial efficacy.