Pharmacodynamics: Which trails are your drugs taking?
April 20th, 2015 by Rumin Zhang
Nature Chemical Biology 11, 382 (2015). doi:10.1038/nchembio.1795
Author: Rumin Zhang
Binding kinetics (BK) has an indispensable role in pharmacodynamics (PD). Incorporating slow BK into a mechanistic PD model is shown to have predictive value for in vitro cellular and in vivo animal antibacterial efficacy.