A chemoproteomic portrait of the oncometabolite fumarate

February 4th, 2019 by Rhushikesh A. Kulkarni

A chemoproteomic portrait of the oncometabolite fumarate

A chemoproteomic portrait of the oncometabolite fumarate, Published online: 04 February 2019; doi:10.1038/s41589-018-0217-y

Chemoproteomic mapping of fumarate sensitive cysteines in a hereditary leiomyomatosis and renal cell carcinoma cell line revealed a critical cysteine in the protein–protein interaction interface of the SWI–SNF complex.