Thermodynamics of Binding of Structurally Similar Ligands to Histone Deacetylase 8 Sheds Light on Challenges in the Rational Design of Potent and Isozyme-Selective Inhibitors of the Enzyme

November 26th, 2014 by Raushan K. Singh, Takayoshi Suzuki, Tanmay Mandal, Narayanaganesh Balsubramanian, Manas Haldar, Dustin J. Mueller, Jerrod A. Strode, Gregory Cook, Sanku Mallik and D. K. Srivastava

TOC Graphic

DOI: 10.1021/bi500711x