XFELs open a new era in structural chemical biology

November 17th, 2015 by Petra Fromme

Nature Chemical Biology 11, 895 (2015). doi:10.1038/nchembio.1968

Author: Petra Fromme

X-ray crystallography, the workhorse of structural biology, has been revolutionized by the advent of serial femtosecond crystallography using X-ray free electron lasers. Here, the fast pace and history of discoveries are discussed together with current challenges and the method's great potential to make new structural discoveries, such as the ability to generate molecular movies of biomolecules at work.