Cancer therapy: Altering mitochondrial properties
January 17th, 2014 by Paolo Pinton
Nature Chemical Biology 10, 89 (2014). doi:10.1038/nchembio.1440
Authors: Paolo Pinton & Guido Kroemer
The mitochondrial permeability transition pore (mPTP) is a multiprotein complex that regulates cell death in multiple pathological conditions. The discovery of new critical components of the mPTP and the identification of anticancer drugs acting on mPTP opens new frontiers for mitochondrial medicine.