Small molecules that target group II introns are potent antifungal agents

October 15th, 2018 by Olga Fedorova

Small molecules that target group II introns are potent antifungal agents

Small molecules that target group II introns are potent antifungal agents, Published online: 15 October 2018; doi:10.1038/s41589-018-0142-0

High-throughput screening followed by an examination of structure–activity relationship-based optimization resulted in the identification of potent small-molecule inhibitors of group IIB intron splicing in fungal organisms.
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