Cargo adaptors regulate stepping and force generation of mammalian dynein–dynactin
September 9th, 2019 by Mohamed M. Elshenawy
Nature Chemical Biology, Published online: 09 September 2019; doi:10.1038/s41589-019-0352-0
Single-molecule analysis revealed that the velocity and force generation of the mammalian dynein–dynactin complex is regulated by activating adaptors and tail–tail interactions between two dyneins.