Cargo adaptors regulate stepping and force generation of mammalian dynein–dynactin

September 9th, 2019 by Mohamed M. Elshenawy

Nature Chemical Biology, Published online: 09 September 2019; doi:10.1038/s41589-019-0352-0

Single-molecule analysis revealed that the velocity and force generation of the mammalian dynein–dynactin complex is regulated by activating adaptors and tail–tail interactions between two dyneins.
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