Designer protein assemblies with tunable phase diagrams in living cells

July 13th, 2020 by Meta Heidenreich

Nature Chemical Biology, Published online: 13 July 2020; doi:10.1038/s41589-020-0576-z

A synthetic phase separation system consisting of two protein components with tunable parameters was developed to visualize and characterize phase diagrams in living cells, revealing that increasing the interaction affinity enhances phase separation and the viscosity of condensates in vivo.
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