Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase

February 15th, 2019 by Maximilian Fottner

Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase

Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase, Published online: 15 February 2019; doi:10.1038/s41589-019-0227-4

A method combining genetic-code expansion, bioorthogonal Staudinger reduction and sortase-mediated transpeptidation enables site-specific and orthogonal modification of proteins with ubiquitin and SUMO in vitro and in living cells.
  • Posted in Nat Chem Biol, Publications
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