Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β<sub>2</sub>AR partial agonist

November 30th, 2018 by Matthieu Masureel

Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist

Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β<sub>2</sub>AR partial agonist, Published online: 30 November 2018; doi:10.1038/s41589-018-0182-5

Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist
  • Posted in Nat Chem Biol, Publications
  • Comments Off on Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β<sub>2</sub>AR partial agonist

Structural insights into binding specificity, efficacy and bias of a β<sub>2</sub>AR partial agonist

October 16th, 2018 by Matthieu Masureel

Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist

Structural insights into binding specificity, efficacy and bias of a β<sub>2</sub>AR partial agonist, Published online: 16 October 2018; doi:10.1038/s41589-018-0145-x

The active-state structure of a GPCR occupied by a partial agonist, β2AR with salmeterol, together with mutagenesis and biophysical studies, explains this ligand's unusual pharmacological profile.
  • Posted in Nat Chem Biol, Publications
  • Comments Off on Structural insights into binding specificity, efficacy and bias of a β<sub>2</sub>AR partial agonist

Protonation drives the conformational switch in the multidrug transporter LmrP

December 8th, 2013 by Matthieu Masureel

Nature Chemical Biology 10, 149 (2014). doi:10.1038/nchembio.1408

Authors: Matthieu Masureel, Chloé Martens, Richard A Stein, Smriti Mishra, Jean-Marie Ruysschaert, Hassane S Mchaourab & Cédric Govaerts

  • Posted in Nat Chem Biol, Publications
  • Comments Off on Protonation drives the conformational switch in the multidrug transporter LmrP