Imaging and targeting LOX-mediated tissue remodeling with a reactive collagen peptide

July 12th, 2021 by Matthew R. Aronoff

Nature Chemical Biology, Published online: 12 July 2021; doi:10.1038/s41589-021-00830-6

Collagen cross-linking, mediated by lysyl oxidases (LOX), is critical for the stability of the extracellular matrix. Aldehyde-reactive sensors and collagen peptide probes for monitoring LOX activity enable direct in vivo imaging of collagen maturation.
  • Posted in Nat Chem Biol, Publications
  • Comments Off on Imaging and targeting LOX-mediated tissue remodeling with a reactive collagen peptide