Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases

January 8th, 2018 by Matthew Jenner

Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases

Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases, Published online: 08 January 2018; doi:10.1038/nchembio.2549

A combination of biochemical and structural techniques allows the characterization of a novel docking domain in polyketide synthases, which is structurally disordered and facilitates association of subunits at ketosynthase–dehydratase junctions.
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