Molecular basis for fibroblast growth factor 23 <i>O</i>-glycosylation by GalNAc-T3

January 13th, 2020 by Matilde de las Rivas

Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0444-x

Polypeptide GalNAc-transferase T3 catalyzes the specific glycosylation of threonine-178 of fibroblast growth factor 23, and structural insights reveal a unique lectin-based mechanism of substrate recognition.
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