SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate

September 6th, 2018 by Mary E. Matyskiela

SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate

SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate, Published online: 06 September 2018; doi:10.1038/s41589-018-0129-x

Thalidomide-induced degradation of the transcription factor SALL4 in a cereblon-dependent manner provides an explanation for the teratogenic effects.
  • Posted in Nat Chem Biol, Publications
  • Comments Off on SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate