Metabolism: A new layer of glycolysis

July 19th, 2016 by Maria V Liberti

Nature Chemical Biology 12, 577 (2016). doi:10.1038/nchembio.2133

Authors: Maria V Liberti & Jason W Locasale

Glucose metabolism has long been thought to operate with exquisite specificity and near-optimal efficiency. New findings show, however, that two glycolytic enzymes produce minor products that inhibit other enzymes involved in central carbon metabolism unless they are further metabolized by a novel enzyme.