Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation

January 20th, 2020 by Lingfeng Chen

Nature Chemical Biology, Published online: 20 January 2020; doi:10.1038/s41589-019-0455-7

X-ray crystallography, solution NMR and biochemical and cell-based analyses reveal a model where catalytically repressed receptor tyrosine kinases accomplish activation loop (A-loop) tyrosine transphosphorylation.
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