<i>Legionella</i> effector SetA as a general O-glucosyltransferase for eukaryotic proteins

January 7th, 2019 by Ling Gao

Legionella effector SetA as a general O-glucosyltransferase for eukaryotic proteins

<i>Legionella</i> effector SetA as a general O-glucosyltransferase for eukaryotic proteins, Published online: 07 January 2019; doi:10.1038/s41589-018-0189-y

A chemoenzymatic tagging approach was developed and identified eukaryotic host proteins that are O-glycosylated by SetA from Legionella. The SetA-consensus motif was applied to recombinant proteins yielding a site-specific O-glucosylation method.
  • Posted in Nat Chem Biol, Publications
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