Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
May 1st, 2017 by Linda Lauinger
Nature Chemical Biology 13, 709 (2017). doi:10.1038/nchembio.2370
Authors: Linda Lauinger, Jing Li, Anton Shostak, Ibrahim Avi Cemel, Nati Ha, Yaru Zhang, Philipp E Merkl, Simon Obermeyer, Nicolas Stankovic-Valentin, Tobias Schafmeier, Walter J Wever, Albert A Bowers, Kyle P Carter, Amy E Palmer, Herbert Tschochner, Frauke Melchior, Raymond J Deshaies, Michael Brunner & Axel Diernfellner