Membrane curvature bends the laws of physics and chemistry

October 20th, 2015 by Lars Iversen

Nature Chemical Biology 11, 822 (2015). doi:10.1038/nchembio.1941

Authors: Lars Iversen, Signe Mathiasen, Jannik Bruun Larsen & Dimitrios Stamou

A 'chemical biology of cellular membranes' must capture the way that mesoscale perturbations tune the biochemical properties of constituent lipid and protein molecules and vice versa. Whereas the classical paradigm focuses on chemical composition, dynamic modulation of the physical shape or curvature of a membrane is emerging as a complementary and synergistic modus operandi for regulating cellular membrane biology.