Affinity selection and sequencing

March 18th, 2019 by Kit S. Lam

Affinity selection and sequencing

Affinity selection and sequencing, Published online: 18 March 2019; doi:10.1038/s41589-019-0253-2

Powerful combinatorial peptide library methods allow the discovery of peptide leads from diverse libraries. A new platform based on tandem mass spectrometry peptide sequencing coupled with high-performance size-exclusion chromatography enables identification of high-affinity peptidic ligands from focused libraries.