Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis
May 6th, 2019 by Kazuma Sakamoto
Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis
Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis, Published online: 06 May 2019; doi:10.1038/s41589-019-0274-x
Sulfation of chondroitin sulfate and heparan sulfate dictates their abilities to promote axon growth via regulating the binding to the phosphatase PTPRσ and the consequences on phosphorylation of the cortactin component of the autophagy machinery.