Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis

May 6th, 2019 by Kazuma Sakamoto

Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis

Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis, Published online: 06 May 2019; doi:10.1038/s41589-019-0274-x

Sulfation of chondroitin sulfate and heparan sulfate dictates their abilities to promote axon growth via regulating the binding to the phosphatase PTPRσ and the consequences on phosphorylation of the cortactin component of the autophagy machinery.
  • Posted in Nat Chem Biol, Publications
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