A tail of CRY selectivity

May 22nd, 2020 by Julia Lara

Nature Chemical Biology, Published online: 22 May 2020; doi:10.1038/s41589-020-0531-z

The discovery of selective modulators of two Cryptochrome isoforms, CRY1 and CRY2, permits a deeper understanding of how circadian clock proteins impact diverse aspects of our daily 24-h rhythms and how this intersects with metabolic pathways relevant to disease.