Drug discovery: Controlling protein SUMOylation

October 18th, 2017 by John S Schneekloth Jr

Drug discovery: Controlling protein SUMOylation

Nature Chemical Biology, Published online: 18 October 2017; doi:10.1038/nchembio.2496

A potent and selective inhibitor of protein SUMOylation, a ubiquitin-like post-translational modification, has been developed, shedding light on the potential for developing new classes of anticancer therapeutics.