Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase

June 25th, 2018 by Jiasong Li

Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase

Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase, Published online: 25 June 2018; doi:10.1038/s41589-018-0085-5

Engineered variants of cysteine dioxygenase containing a halogen-substituted tyrosine analog provide insights into the process of Cys–Tyr cross-link formation and indicate that the enzyme can catalyze oxidative cleavage of a carbon–fluorine bond.
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