Production of Tyrian purple indigoid dye from tryptophan in <i>Escherichia coli</i>

November 2nd, 2020 by Jeongchan Lee

Nature Chemical Biology, Published online: 02 November 2020; doi:10.1038/s41589-020-00684-4

A two-cell setup containing tryptophanase, a flavin-dependent monooxygenase and a regiospecific halogenase (linked to a flavin reductase as a solubility tag) enables the production of 6,6'-dibromoindigo and other indigoid dyes in Escherichia coli.
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