IFITM3 directly engages and shuttles incoming virus particles to lysosomes

January 14th, 2019 by Jennifer S. Spence

IFITM3 directly engages and shuttles incoming virus particles to lysosomes

IFITM3 directly engages and shuttles incoming virus particles to lysosomes, Published online: 14 January 2019; doi:10.1038/s41589-018-0213-2

Live-cell imaging and virus trafficking studies show that the host innate immune receptor IFITM3 localizes with endocytic vesicles that fuse with incoming viruses to ultimately enhance their traffic to lysosomes.
  • Posted in Nat Chem Biol, Publications
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