ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth

April 29th, 2021 by Jarrett R. Remsberg

Nature Chemical Biology, Published online: 29 April 2021; doi:10.1038/s41589-021-00785-8

ABD957 is a potent and selective inhibitor of the ABHD17 family of depalmitoylases that disrupts N-Ras signaling in human acute myeloid leukemia cells and can synergize with MEK inhibition.
  • Posted in Nat Chem Biol, Publications
  • Comments Off on ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth