A kinetic view of GPCR allostery and biased agonism

August 18th, 2017 by J Robert Lane

Nature Chemical Biology 13, 929 (2017). doi:10.1038/nchembio.2431

Authors: J Robert Lane, Lauren T May, Robert G Parton, Patrick M Sexton & Arthur Christopoulos

A new mechanism of allostery in a G protein–coupled receptor dimer

August 10th, 2014 by J Robert Lane

Nature Chemical Biology 10, 745 (2014). doi:10.1038/nchembio.1593

Authors: J Robert Lane, Prashant Donthamsetti, Jeremy Shonberg, Christopher J Draper-Joyce, Samuel Dentry, Mayako Michino, Lei Shi, Laura López, Peter J Scammells, Ben Capuano, Patrick M Sexton, Jonathan A Javitch & Arthur Christopoulos