Genetic engineering: Chemical control for CRISPR editing
November 7th, 2016 by Isaac B Hilton
Nature Chemical Biology 13, 2 (2017). doi:10.1038/nchembio.2243
Authors: Isaac B Hilton & Charles A Gersbach
New approaches allow tight control over Cas9 activity using chemical induction. These studies expand the ability to rapidly induce and suppress Cas9-mediated nuclease activity and conditionally modulate the multiplex regulation of endogenous gene expression.