Structural basis of sequence-specific Holliday junction cleavage by MOC1

October 14th, 2019 by Huajian Lin

Nature Chemical Biology, Published online: 14 October 2019; doi:10.1038/s41589-019-0377-4

Crystal structural and biochemical analysis of the chloroplast-localized Holliday junction (HJ) resolvase MOC1 in Zea mays reveals that ZmMOC1 uses a unique β-hairpin structure and a two-metal ion catalysis mechanism to recognize and cleave HJs.
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