A quantitative method for proteome reallocation using minimal regulatory interventions

July 13th, 2020 by Gustavo Lastiri-Pancardo

Nature Chemical Biology, Published online: 13 July 2020; doi:10.1038/s41589-020-0593-y

An econometric model built on regulatory networks and calibrated by proteomics data identifies nonessential transcription factors that when deleted in Escherichia coli result in a strain with an expanded proteome for engineering applications.
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