Optogenetics: Switching with red and blue

May 17th, 2017 by Fuun Kawano

Nature Chemical Biology 13, 573 (2017). doi:10.1038/nchembio.2387

Authors: Fuun Kawano, Fan Shi & Masayuki Yazawa

Multiple optogenetic technologies are required to control biological activity simultaneously with different colors of light. Optimizing a near-infrared-induced heterodimerization system, which can be combined with blue-light-controlled domains, enables precise spatiotemporal control of target molecules in live mammalian cells.

A photoactivatable Cre–loxP recombination system for optogenetic genome engineering

October 10th, 2016 by Fuun Kawano

Nature Chemical Biology 12, 1059 (2016). doi:10.1038/nchembio.2205

Authors: Fuun Kawano, Risako Okazaki, Masayuki Yazawa & Moritoshi Sato

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