A genetics-free method for high-throughput discovery of cryptic microbial metabolites

January 7th, 2019 by Fei Xu

A genetics-free method for high-throughput discovery of cryptic microbial metabolites

A genetics-free method for high-throughput discovery of cryptic microbial metabolites, Published online: 07 January 2019; doi:10.1038/s41589-018-0193-2

A combination of elicitor screening to induce expression of silent biosynthetic gene clusters with imaging mass spectrometry to visualize the resulting metabolome enables the discovery of nine cryptic natural products.
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