Translation: An O-GlcNAc stamp of approval

March 16th, 2015 by Evan T Powers

Nature Chemical Biology 11, 307 (2015). doi:10.1038/nchembio.1777

Author: Evan T Powers

Cytosolic proteins can be modified cotranslationally by the installation of O-GlcNAc groups onto serine and threonine residues. This modification suppresses cotranslational ubiquitination and stabilizes proteins against proteasomal degradation.